What are the categories of dental collagen products?

Dental collagen products are diverse and have a wide range of applications. For example, dental collagen wound dressing plugs are used to control bleeding, and absorbable forms of collagen are used to dress oral wounds, close grafts, and extraction sites, and promote healing. Dental collagen membranes have also been used in periodontal and implant treatments as a barrier to prevent epithelial migration and to allow regenerative cells to refill defective areas. Next are some details.

Here is the content list:

• Dental collagen membranes

• Dental collagen membranes for GTR

• Dental collagen bone graft substitutes

• Collagen dressings

Dental collagen membranes

In dentistry, dental collagen membranes are used for periodontal reconstruction in a procedure called guided tissue regeneration (GTR). Dental collagen membranes are also used to stop the migration of rapidly growing gingival epithelial cells into the wound. the GTR procedure uses a barrier device placed between the periodontal flap and the bone defect to maintain space for the defect to have regenerative potential. The first commercially available membranes were made of expanded polytetrafluoroethylene (ePTFE) and were non-absorbable.

A variety of resorbable barrier materials are now available that do not require secondary surgery. There are a variety of materials used to prepare bioresorbable membranes, such as polyglycolic acid, polylactic acid, dura mater, pericardium, oxidized cellulose, rubber barriers, and laminar bone. However, collagen has proven to be particularly suitable for GTR applications because it is chemotactic for periodontal ligament fibroblasts, acts as a barrier for migrating epithelial cells, provides hemostasis, and acts as a fibrous scaffold for early vascular and tissue inward growth.

Dental collagen membranes for GTR

The various types of dental collagen membranes used for GTR treatment come from different animal sources - such as bovine, porcine, or equine - and are obtained from various sites, such as tendon or dermis. They are obtained from either type I or type III collagen or both.

Studies have shown that bone may grow into the pores and interstices of the membrane at sites where the membrane is in close contact with bone. Bone is deposited directly on the pore walls, almost filling the pores and even penetrating membranes composed of perfectly bioinert materials with osteoconductive properties. This phenomenon is found in collagen-based barrier membranes, especially if they are cross-linked. Although an ideal GTR membrane has not yet been developed, those currently available dental collagen membranes made of collagen appear to provide many of the desired properties.

Dental collagen bone graft substitutes

Dental collagen bone graft substitutes have been used as implantable carriers for osteoinductive proteins. Collagen is used in combination with other polymers or chemicals for bone augmentation procedures. Demineralized collagen is used as a bone graft material for the treatment of acquired and congenital defects alone or in combination with hydroxyapatite.

Collagen dressings

Collagen is also used in dentistry as a wound dressing. Several key features of collagen have led to the development of collagen dressings. The first is its structural and functional significance in wound repair. Then, also its hydrophilicity, which can be attributed to a molecular structure characterized by a high content of diamino carboxylic acid and carbohydrate fraction, which provides a surface geometry well suited for cell adhesion. Another factor that promotes the attraction of fibroblasts to collagen implants is the presence of glycoprotein-like fibronectin on the cell surface. These molecules have a high affinity for collagen and are specifically attached to specific regions of the collagen surface.

There are two main forms of collagen wound dressings. One of them is the dental collagen wound dressing sponge. Dental collagen wound dressing sponges form a 3-D structure consisting of a combination of macropores or channels, interchannel communication, and connective tissue macromolecules to enhance infiltration and cell growth of wound tissue in vivo. Dental collagen wound dressing sponges have been used as temporary and permanent coverings. Inward cell growth within the sponge depends on the porosity and the presence of fibrous structures.

Guangdong Victory Biotech Co., Ltd manufactures a wide range of dental collagen products. If you are interested in our products, please contact us.