The physical and chemical properties of Implant Grade Atelo Gelatin

Implant Grade Atelo Gelatin is the product of collagen denaturation. It belongs to the category of protein macromolecules. It has similar properties to protein macromolecules. However, due to the particularity of the molecular structure, its physical and chemical properties are unique. Next, let us understand the physical and chemical properties of Implant Grade Atelo Gelatin. Here are some answers.

Here is the content list:

l Isoelectric point.

l Surface activity.

l Gel strength.

Isoelectric point.

According to the survey, the isoelectric point of acid-processed gelatin is generally in the range of pH 7.5-9, while the isoelectric point of alkaline-processed gelatin is in the range of pH 4.8-5.0. Implant Grade Atelo Gelatin prepared by these two different processes will have incompatibility when mixed, such as emulsion layering, reduced transparency, agglomeration, and so on. Therefore, when mixing Medical Grade Atelocollagen Products, pay attention to the isoelectric point of Implant Grade Atelo Gelatin and the pH value during use.

Surface activity.

The polypeptide chain composed of amino acids has a hydrophilic region and a hydrophobic region, so the Implant Grade Atelo Gelatin has the same surface activity as some surfactants. Studies have shown that the surface tension of the Implant Grade Atelo Gelatin solution is related to its concentration, temperature, pH, and other factors. When the gelatin solution has a concentration of 1% or less and a temperature of 10 to 45°C, it is measured at the interface where the solution is formed for less than 1 hour, and it is found that the surface tension is the highest between pH=2 to 3. And its minimum surface tension appears at the isoelectric point. The study also pointed out that the surface tension decreases linearly with temperature below 30°C, and drops more sharply between 30°C and 40°C. However, when the temperature is above 40°C, it will decrease further as the temperature increases, and the rate of decrease is greater than that of pure water. Where there is aging, the surface tension generally decreases with time.

Gel strength.

When the warm aqueous gelatin solution cools, its viscosity gradually increases. If the concentration is high enough and the temperature is low enough, the aqueous gelatin solution will turn into a gel. Gelatin gel is similar to a solid substance, capable of maintaining its shape and having elasticity. Gelatin gel can be reversibly transformed into a solution state after being heated. These are the unparalleled characteristics of Implant Grade Atelo Gelatin. The gelatin solution is cooled at low temperature until gelation occurs and aged at a certain low temperature for a certain period, and then the stable gel strength value can be measured. The gel strength of gelatin is related to the molecular weight and distribution of gelatin, amino acid composition, and technological process. Gelatin for different purposes requires different gel strength.

Our official website is https://www.victorybio.com/. If you are engaged in a related profession, or are interested in our Implant Grade Atelo Gelatin products, or have any other needs, please feel free to contact us. We have developed a variety of atelocollagen products ranging from materials to finished collagen products, including Fibrillar Atelocollagen Powder, cosmetic grade Water Soluble Atelocollagen Solution, which can be widely used in implantable medical and skincare applications. As a professional atelocollagen manufacturer, we have been providing collagen materials or processed products to global customers, assisting them in developing and improving new product processes, technologies, and customized raw materials.